The SERPINA1 gene provides instructions for making a protein called alpha-1 antitrypsin, which is a type of serine protease inhibitor (serpin). Learn about this gene and related health conditions.

Nov 14, 2025 · Complete information for SERPINA1 gene (Protein Coding), Serpin Family A Member 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The …

Oct 18, 2022 · Differences (mutations) in a specific gene cause Alpha-1 antitrypsin deficiency. The SERPINA1 gene makes a protein called Alpha-1 antitrypsin (AAT) that protects your lungs from …

Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene. A protease inhibitor, it is also known …

The SERPINA1 gene that encodes alpha-1 antitrypsin (AAT) is a highly polymorphic 12.2kb gene clustered with other serpin genes on the long arm of chromosome 14 at position 32.13 (14q32.13), …

The SERPINA1 gene encodes alpha-1-antitrypsin (AAT), also known as protease inhibitor (PI), a major plasma serine protease inhibitor. AAT complexes predominantly with elastase, but also with trypsin, …

The SERPINA1 gene provides instructions for making a protein called alpha-1 antitrypsin (AAT), which protects the body from damage by its immune cells. If you have Alpha-1, you inherited two copies of …

Dec 20, 2023 · The Serpina1 gene is responsible for producing alpha-1 antitrypsin, a protein that helps protect the lungs from damage caused by inflammation and infection.

Gene: SERPINA1 ENSG00000197249 Description serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 [Source:HGNC Symbol;Acc: 8941]

SERPINA1 Gene ... Functional Associations SERPINA1 has 17,514 functional associations with biological entities spanning 8 categories (molecular profile, organism, disease, phenotype or trait, …